2,869
edits
No edit summary |
|||
Line 23: | Line 23: | ||
==== Toxicity ==== | ==== Toxicity ==== | ||
Ibotenic acid is known to be a neurotoxin, acting via the NMDA receptor and metabotropic glutamate receptor. Ibotenic acid can be converted to muscimol via decarboxylation. This can be performed using a combination of heat and acid-catalysis with the potential for adding decarboxylasing enzymes such as milk / lactobacillus derivatives which contain glutamate decarboxylase. | |||
==== Preparation ==== | ==== Preparation ==== | ||
Line 46: | Line 44: | ||
==== Dose ==== | ==== Dose ==== | ||
A medium-size fresh carpophore with a cap diameter of 10-15 cm weighs about 60-70 g. According to literature reports<ref name=":0" />, Siberian mushroom eaters used for moderate effects 1-4 dried mushrooms and 5-10 was considered immoderate use. For dosing, start with a small amount such as 1/4 or 1 teaspoon while you are awake, and see how it affects you. Each new separate day while you are awake, increase the amount by a little until you then have the dose or dose range you want to experiment with. If your liquid is extra potent you can experiment with this same liquid at expected dosing for several weeks (or all year if used infrequently). | A medium-size fresh carpophore with a cap diameter of 10-15 cm weighs about 60-70 g. According to literature reports<ref name=":0" />, Siberian mushroom eaters used for moderate effects 1-4 dried mushrooms and 5-10 was considered immoderate use. For dosing, start with a small amount such as 1/4 or 1 teaspoon while you are awake, and see how it affects you. Each new separate day while you are awake, increase the amount by a little until you then have the dose or dose range you want to experiment with. If your liquid is extra potent you can experiment with this same liquid at expected dosing for several weeks (or all year if used infrequently). | ||
==== '''Contraindications''' ==== | |||
It may be harmful to combine Amanita muscaria constituents with other GABAergic depressants such as alcohol, benzodiazepines or barbiturates. Amanita muscaria mushrooms are not known to be addictive or dependence-forming, and reports even show that desire to redose goes down with usage, though there is no research on this topic. | |||
'''References''' | '''References''' | ||
<references /> | <references /> |