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[[File:Effects of psilocybin.png|alt=psilocybin effects at different doses.|thumb|'''Figure 3'''. A circular graph plotting the subjective effects of various increasing doses of psilocybin.]] | [[File:Effects of psilocybin.png|alt=psilocybin effects at different doses.|thumb|'''Figure 3'''. A circular graph plotting the subjective effects of various increasing doses of psilocybin.]] | ||
Whether these effects are experienced is dependent on dosage (see '''Figure 3'''), which at its lowest perceptual dose is around 10µg. | Compared to amphetamines, which increase the firing of neurons in more typical, synchronized patterns, psilocybin disrupts brain activity both locally and regionally, leading to a desynchronization of neurons that usually fire together.<ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11291293/ Siegel, J. S., et al. (2024). "Psilocybin desynchronizes the human brain." Nature 632(8023): 131-138.]</ref> | ||
Whether these effects are experienced is dependent on dosage (see '''Figure 3'''), which at its lowest perceptual dose is around 10µg. | |||
=== Long Term Effects === | === Long Term Effects === |