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MDMA: Difference between revisions
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MDMA works by altering the brains [[neurochemistry]]: | MDMA works by altering the brains [[neurochemistry]]: | ||
* Increasing (↑) dopamine by reducing how it | * Increasing (↑) '''dopamine''' by reducing how it is reabsorbed post release. | ||
* Increasing (↑↑↑) serotonin by reducing how it | * Increasing (↑↑↑) '''serotonin''' by reducing how it is reabsorbed post release. | ||
* Increasing oxytocin (neuromodulator) concentration. | * Increasing '''oxytocin''' (neuromodulator) concentration. | ||
==== Neurophysiology ==== | ==== Neurophysiology ==== | ||
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=== Short Term === | === Short Term === | ||
[[File:MDMA Time Effect Curve.png|alt=The dynamic of an MDMA trip is not linear, it takes effect at 30-45 minutes and peaks at 2 hours.|thumb|'''Figure 1'''. MDMA Time-Effect Curve]] | [[File:MDMA Time Effect Curve.png|alt=The dynamic of an MDMA trip is not linear, it takes effect at 30-45 minutes and peaks at 2 hours.|thumb|'''Figure 1'''. MDMA Time-Effect Curve]] | ||
When ingested orally, the effects of MDMA typically begin within 30 to 45 minutes and can last for three to six hours. The experience induced by MDMA is usually milder compared to traditional psychedelics. It is | When ingested orally, the effects of MDMA typically begin within 30 to 45 minutes and can last for three to six hours. The experience induced by MDMA is usually milder compared to traditional psychedelics. It is characterised by heightened feelings of excitement, empathy, and a sense of trust. Unlike substances like [[ketamine]], which are known for their dissociative effects, [[MDMA]] is often described as having affiliative properties, promoting a sense of connection and sociability. | ||
=== Long Term === | === Long Term === | ||