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[[File:Neuroplasticity.png|alt=Neuroplasticity|thumb|'''Figure 1'''. Neuroplasticity Vs Age<ref name=":0" />.]] | [[File:Neuroplasticity.png|alt=Neuroplasticity|thumb|'''Figure 1'''. Neuroplasticity Vs Age<ref name=":0" />.]] | ||
''' | '''As we age, it is difficult to teach the ''old dog'' new tricks.''' This challenge stems from the decline in neuroplasticity, the brain's ability to alter its default state as we age<ref name=":2">'''Aging-Related Dysfunction of Striatal Cholinergic Interneurons Produces Conflict in Action Selection''', Miriam Matamales, Zala Skrbis, Robert J. Hatch, Bernard W. Balleine. Neuron Journal. Accesed on 7th October 2023 via: <nowiki>https://www.cell.com/neuron/pdf/S0896-6273(16)00185-9.pdf</nowiki></ref>. Despite this natural decline, there's a silver lining – a vast amount of scientific studies have uncovered that [[psychedelics]] have the unique ability to temporarily reopen a neuroplastic window, offering a potential avenue for change. | ||
[[File:The Fused Brain.png|alt=The Fused Brain|thumb|'''Figure 2'''. The fused brain<ref name=":1">'''The older adult brain is less modular, more integrated, and less efficient at rest: A systematic review of large-scale resting-state functional brain networks in aging'''. Hamish A. Deery,Robert Di Paolo,Chris Moran,Gary F. Egan,Sharna D. Jamadar First published: 15 September 2022 https://doi.org/10.1111/psyp.14159. Accessed on 4th October 2022 via https://onlinelibrary.wiley.com/doi/10.1111/psyp.14159</ref>]] | [[File:The Fused Brain.png|alt=The Fused Brain|thumb|'''Figure 2'''. The fused brain<ref name=":1">'''The older adult brain is less modular, more integrated, and less efficient at rest: A systematic review of large-scale resting-state functional brain networks in aging'''. Hamish A. Deery,Robert Di Paolo,Chris Moran,Gary F. Egan,Sharna D. Jamadar First published: 15 September 2022 https://doi.org/10.1111/psyp.14159. Accessed on 4th October 2022 via https://onlinelibrary.wiley.com/doi/10.1111/psyp.14159</ref>]] | ||
When young, humans are extremely neuroplastic | When young, humans are extremely neuroplastic meaning when an experience demands, it doesn't take much effort to change the brains default behaviour. Neuroplasticity declines as we age (see '''Figure 1''')<ref name=":2" /><ref name=":0">'''Changes in plasticity across the lifespan''': Cause of disease and target for intervention. Publish 10 April 2015, accessed on 3rd March 2022, via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392917/. '''[[Changes in plasticity across the lifespan: Cause of disease and target for intervention|''<u>Read an AI summary.</u>'']]'''</ref><ref>'''Molecular aging of the brain, neuroplasticity, and vulnerability to depression and other brain-related disorders.''' Dialogues in Clinical Neuroscience. Volume 15, 2013 - Issue 1. Etienne Sibille Pages 53-65 | Published online: 01 Apr 2022. Accessed 19th Jun 2022 via https://www.tandfonline.com/doi/full/10.31887/DCNS.2013.15.1/esibille</ref>, leading to a more ''fused'' brain (see '''Figure 2''')<ref name=":1" />. Recent studies have shown neuroplasticity can be temporarily improved by inducing [[Pivotal mental state|pivotal mental states]] via the use of psychedelics. | ||
This decline in neuroplasticity was eloquently described in three points by Douglas Adams reflecting on our relationship with technology: | This decline in neuroplasticity was eloquently described in three points by Douglas Adams reflecting on our relationship with technology: |