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Dosage is performed in the following stages...<ref>'''MDMA-assisted therapy for moderate to severe PTSD''': a randomized, placebo-controlled phase 3 trial, Jennifer M. Mitchell, Published: 14 September 2023, accessed 4 Dec via https://www.nature.com/articles/s41591-023-02565-4</ref> | Dosage is performed in the following stages...<ref>'''MDMA-assisted therapy for moderate to severe PTSD''': a randomized, placebo-controlled phase 3 trial, Jennifer M. Mitchell, Published: 14 September 2023, accessed 4 Dec via https://www.nature.com/articles/s41591-023-02565-4</ref> | ||
1. Recruitment and medical screening. | 1. Recruitment and medical screening. Start tapering of other medicines if needed. | ||
2. Prep sessions 1 and spaced over 2 weeks. | 2. Prep sessions 1 and spaced over 2 weeks. | ||
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== Effects == | == Effects == | ||
MDMA when taken by mouth, effects begin in 30 to 45 minutes | [[File:MDMA Time Effect Curve.png|alt=The dynamic of an MDMA trip is not linear, it takes effect at 30-45 minutes and peaks at 2 hours.|thumb|'''Figure 1'''. MDMA TIme-Effect Curve]] | ||
MDMA when taken by mouth, effects begin in 30 to 45 minutes and last three to six hours. The medicine provides an experience that is mellower than with other [[psychedelics]], creating feelings of empathy. May enhance fear extinction, resulting in a shift in perspective and improved ability to process traumatic memories. May provide insight into cognition, emotional regulation, and coping strategies. Causes dopamine release that is linked to addictive behaviors. | |||
==== MDMA Comedown ==== | ==== MDMA Comedown ==== |