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MADRS: Difference between revisions
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Each item yields a score of 0 to 6; the overall score thus ranges from 0 to 60. One of the largest psychedelic ([[psilocybin]]) studies has found that a 2.5mg dose can lead to a 6.6 point reduction in MADRS score<ref>'''COMPASS Pathways announces positive topline results from groundbreaking phase IIb trial of investigational COMP360 psilocybin therapy for treatment-resistant depression.''' November 09, 2021. Accessed on 17th October 2023 via: https://ir.compasspathways.com/news-releases/news-release-details/compass-pathways-announces-positive-topline-results</ref>. | Each item yields a score of 0 to 6; the overall score thus ranges from 0 to 60. One of the largest psychedelic ([[psilocybin]]) studies has found that a 2.5mg dose can lead to a 6.6 point reduction in MADRS score<ref>'''COMPASS Pathways announces positive topline results from groundbreaking phase IIb trial of investigational COMP360 psilocybin therapy for treatment-resistant depression.''' November 09, 2021. Accessed on 17th October 2023 via: https://ir.compasspathways.com/news-releases/news-release-details/compass-pathways-announces-positive-topline-results</ref>. Higher MADRS score indicates more severe depression. Usual cutoff points are: | ||
* 0 to 6: normal /symptom absent | |||
* 7 to 19: mild depression | |||
* 20 to 34: moderate depression | |||
* 35 to 60: severe depression. | |||
=== Role of MADRS in Psychedelic Therapy === | === Role of MADRS in Psychedelic Therapy === | ||