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[[File:Psilocybin chemical structure.jpg|alt=Psilocybin chemical structure|thumb|'''Figure 1'''. Psilocybin chemical structure]] | [[File:Psilocybin chemical structure.jpg|alt=Psilocybin chemical structure|thumb|'''Figure 1'''. Psilocybin chemical structure]] | ||
'''The active [[Psychedelics|psychedelic]] ingredient (when converted to psilocin) found within [[magic mushrooms]]'''. Psilocybin has been found to be | '''The active [[Psychedelics|psychedelic]] ingredient (when converted to psilocin) found within [[magic mushrooms]]'''. Psilocybin has been found to be effective therapy for treatment resistant depression (TRD). | ||
Psilocybin ('''Figure 1''') degrades quickly into its active metabolite psilocin after ingestion. Both psilocin and psilocybin exhibit affinity for a range of serotonin receptors (5-HT1A/B/D/E, 2B, 5, 6, 7) with high affinity for the 5-HT2A receptor. | Psilocybin ('''Figure 1''') degrades quickly into its active metabolite psilocin after ingestion. Both psilocin and psilocybin exhibit affinity for a range of serotonin receptors (5-HT1A/B/D/E, 2B, 5, 6, 7) with high affinity for the 5-HT2A receptor. |