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=== Neuroactivity === | === Neuroactivity === | ||
Lion's Mane contains the pharmacologically active compounds hericenones and erinacines which have been shown to stimulate human nerve growth factor (NGF) synthesis<ref>'''Nerve Growth Factor-Inducing Activity of Hericium erinaceus in 1321N1''', Human Astrocytoma Cells Koichiro MORI, a,c Yutaro OBARA, a,b Mitsuru HIROTA. Department of Cellular Signaling, Graduate School of Pharmaceutical Sciences, Tohoku University, Japan. Accessed on 15th Jul 2023 via <nowiki>https://pubmed.ncbi.nlm.nih.gov/18758067/</nowiki></ref>. | |||
==== Depression ==== | ==== Depression ==== | ||
[[File:Lions mane for depression.jpg|alt=Lions mane for depression|thumb|'''Figure 1'''. Lion's Mane mechanism of action in depression<ref>'''Therapeutic Potential of Hericium erinaceus for Depressive Disorder''' by Pit Shan Chong ,Man-Lung Fung , Kah Hui Wong *ORCID and Lee Wei Lim. School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China. Department of Anatomy, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. Int. J. Mol. Sci. 2020, Accessed 15th July 2023 via: <nowiki>https://www.mdpi.com/1422-0067/21/1/163</nowiki></ref>]] | [[File:Lions mane for depression.jpg|alt=Lions mane for depression|thumb|'''Figure 1'''. Lion's Mane mechanism of action in depression<ref>'''Therapeutic Potential of Hericium erinaceus for Depressive Disorder''' by Pit Shan Chong ,Man-Lung Fung , Kah Hui Wong *ORCID and Lee Wei Lim. School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China. Department of Anatomy, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. Int. J. Mol. Sci. 2020, Accessed 15th July 2023 via: <nowiki>https://www.mdpi.com/1422-0067/21/1/163</nowiki></ref>]] | ||
There is some evidence to suggest that Lion's Mane can be used in the treatment of depression.<ref>'''Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake''' (2010). Mayumi Nagano, Kuniyoshi Shimizu, J-Stage, Biomedical Research. Accessed on 15th July 2023 via: https://doi.org/10.2220/biomedres.31.231</ref> | |||
==== Cognitive Impairment ==== | ==== Cognitive Impairment ==== |