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Psychedelics: Difference between revisions
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<seo title="Psychedelic Medicine" metakeywords="psychedelic drugs list, psychedelic drugs for depression, psychedelic drugs australia, psychedelic drugs literature, psychedelic plant medicine, psychedelic drug used to treat ptsd, psychedelic drug used for depression" metadescription="What is psychedelic medicine?"/><HTML><iframe width="100%" height="450" src="https://www.youtube.com/embed/607F6j5W3sE" title="YouTube video player" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture" allowfullscreen></iframe></HTML> | <seo title="Psychedelic Medicine" metakeywords="psychedelic drugs list, psychedelic drugs for depression, psychedelic drugs australia, psychedelic drugs literature, psychedelic plant medicine, psychedelic drug used to treat ptsd, psychedelic drug used for depression" metadescription="What is psychedelic medicine?"/><HTML><iframe width="100%" height="450" src="https://www.youtube.com/embed/607F6j5W3sE" title="YouTube video player" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture" allowfullscreen></iframe></HTML> | ||
[[File:Psychedelic effect.jpg|alt=This figure is from a 2014 study in the Journal of the Royal Society Interface. The image on the left is of a human brain on a placebo, and the image on the right is of a brain on psilocybin.|thumb|'''Figure 1'''. A 2014 study in the ''Journal of the Royal Society Interface''. The image on the left is of a human brain on a placebo, and the image on the right is of a brain on a psychedelic.]] | [[File:Psychedelic effect.jpg|alt=This figure is from a 2014 study in the Journal of the Royal Society Interface. The image on the left is of a human brain on a placebo, and the image on the right is of a brain on psilocybin.|thumb|'''Figure 1'''. A 2014 study in the ''Journal of the Royal Society Interface''. The image on the left is of a human brain on a placebo, and the image on the right is of a brain on a psychedelic.]] | ||
'''Psychedelics are [[Drugs|medicinal compounds]] that given the correct [[priming]] (set) and [[setting]] have potent anxiolytic, antidepressant and anti addictive effects.''' It is suggested that these effects | '''Psychedelics are [[Drugs|medicinal compounds]] that given the correct [[priming]] (set) and [[setting]] have potent anxiolytic, antidepressant and anti addictive effects.''' It is suggested that these effects arise from induced [[Pivotal Mental States]]. | ||
During the [[Psychedelic Experience|psychedelic experience,]] as shown in the illustrated brain scan to the right ('''Figure 1''') parts of the brain which do not usually communicate with one another start talking, and subconscious inputs open up to the conscious mind. The experience is thought to open a [[Neuroplasticity|neuroplastic]] window giving users an opportunity to correct ruminating thought patterns thought to be the basis of [[Mental Illness|mental illnesses]] such as bipolarity<ref>'''Risks and benefits of psilocybin use in people with bipolar disorder: An international web-based survey on experiences of ‘magic mushroom’ consumption'''. Emma Morton, Kimberly Sakai, and Josh Woolley. Volume 37, Issue . <nowiki>https://doi.org/10.1177/02698811221131997</nowiki>. Accessed 23 Jan 2023 via https://journals.sagepub.com/doi/full/10.1177/02698811221131997</ref>, [[depression]], anxiety. | During the [[Psychedelic Experience|psychedelic experience,]] as shown in the illustrated brain scan to the right ('''Figure 1''') parts of the brain which do not usually communicate with one another start talking, and subconscious inputs open up to the conscious mind. The experience is thought to open a [[Neuroplasticity|neuroplastic]] window giving users an opportunity to correct ruminating thought patterns thought to be the basis of [[Mental Illness|mental illnesses]] such as bipolarity<ref>'''Risks and benefits of psilocybin use in people with bipolar disorder: An international web-based survey on experiences of ‘magic mushroom’ consumption'''. Emma Morton, Kimberly Sakai, and Josh Woolley. Volume 37, Issue . <nowiki>https://doi.org/10.1177/02698811221131997</nowiki>. Accessed 23 Jan 2023 via https://journals.sagepub.com/doi/full/10.1177/02698811221131997</ref>, [[depression]], anxiety. | ||
== History == | == History == | ||
Psychedelic medicine has been mired in [[War on Drugs|taboo]] since the 1970's however, they are now emerging with the advent of [[The Psychedelic Renaissance]] as relatively safe medicine for psychiatric illness. | |||
== Psychedelic Compounds == | == Psychedelic Compounds == | ||
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'''Phenylethylamines''' | '''Phenylethylamines''' | ||
* Mescaline found in the peyote cactus | * Mescaline found in the peyote cactus a Native American [[entheogen]]. | ||
* MDMA and 2C-B synthetic compounds made by the chemist Alexander Shulgin. | * MDMA and 2C-B synthetic compounds made by the chemist Alexander Shulgin. | ||
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* '''Cyclical thought patterns:''' | * '''Cyclical thought patterns:''' | ||
**'''Depression''' - multiple meta analyses results suggest that psychedelic-assisted therapy is effective with minimal adverse effects<ref>'''Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants'''. Nicole L. Galvão-Coelho, Psychopharmacology (Berl). 2021; 238(2): 341–354. Published online 2021 Jan 11. doi: 10.1007/s00213-020-05719-1. Accessed on 16th | **'''Depression''' - multiple meta analyses results suggest that psychedelic-assisted therapy is effective with minimal adverse effects<ref>'''Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants'''. Nicole L. Galvão-Coelho, Psychopharmacology (Berl). 2021; 238(2): 341–354. Published online 2021 Jan 11. doi: 10.1007/s00213-020-05719-1. Accessed on 16th September 2022 via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7826317/pdf/213_2020_Article_5719.pdf</ref><ref>'''''A Meta-Analysis of Placebo-Controlled Trials of Psychedelic-Assisted Therapy'''. Luoma, J. B., Chwyl, C., Bathje, G. J., Davis, A. K., & Lancelotta, R. (2020). Journal of Psychoactive Drugs, 1–11.'' doi:10.1080/02791072.2020.1769878. Accessed on 16th September 2022 via: https://pubmed.ncbi.nlm.nih.gov/32529966/ </ref>, relative to a comparable meta analysis of the effects of 21 traditional antidepressant drugs<ref>'''Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis.''' Andrea Cipriani, MD. Published in the Lancet. February 21, 2018 DOI:<nowiki>https://doi.org/10.1016/S0140-6736(17)32802-7</nowiki></ref>, relative to other treatments psychedelics lack the majority of serious adverse effects. | ||
**'''Obsessive compulsive disorder (OCD)''' | **'''Obsessive compulsive disorder (OCD)''' | ||
*'''Cyclical behavioural patterns:''' | *'''Cyclical behavioural patterns:''' | ||