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===Electroconvulsive Therapy=== | ===Electroconvulsive Therapy=== | ||
When people think of ECT they often think of the film ''One Flew Over the Cuckoo's Nest'', however this was a dramatisation, the modern process is far from what was depicted. Since its introduction in the 1930's, various changes to pulse width, dosing and duration, electrode placement and anesthesia have made the treatment almost unrecognisable<ref>'''Electroconvulsive therapy: a selected review'''. ''Am J Geriatr Psychiatry''. Greenberg RM, Kellner CH. 2005;13(4):268–81.</ref>. Research has shown that 64% to 87% of patients with severe MDD respond to ECT, with response rates as high as 95% for patients with MDD with psychotic features<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193538/</ref>. Furthermore, in otherwise healthy patients with intellectual disability, a retrospective chart review performed at Cambridge university has shown that 79% showed a positive outcome following ECT<ref>https://www.cambridge.org/core/journals/the-psychiatrist/article/use-of-ect-in-patients-with-an-intellectual-disability-review/B2CD9151E5A2B9462BD80175E63A9CB0</ref>. There is some evidence to suggest that ECT causes similar long and short term effects to psychedelics in some in vivo case studies<ref>Psychotic symptoms as a complication of electroconvulsive therapy – a case report Anna Antosik-Wójcińska, Magdalena Chojnacka, Łukasz Święcicki Affective Disorders Unit, Second Department of Psychiatry, Institute of Psychiatry and Neurology in Warsaw</ref><ref> | When people think of ECT they often think of the film ''One Flew Over the Cuckoo's Nest'', however this was a dramatisation, the modern process is far from what was depicted. Since its introduction in the 1930's, various changes to pulse width, dosing and duration, electrode placement and anesthesia have made the treatment almost unrecognisable<ref>'''Electroconvulsive therapy: a selected review'''. ''Am J Geriatr Psychiatry''. Greenberg RM, Kellner CH. 2005;13(4):268–81.</ref>. Research has shown that 64% to 87% of patients with severe MDD respond to ECT, with response rates as high as 95% for patients with MDD with psychotic features<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193538/</ref>. Furthermore, in otherwise healthy patients with intellectual disability, a retrospective chart review performed at Cambridge university has shown that 79% showed a positive outcome following ECT<ref>https://www.cambridge.org/core/journals/the-psychiatrist/article/use-of-ect-in-patients-with-an-intellectual-disability-review/B2CD9151E5A2B9462BD80175E63A9CB0</ref>. There is some evidence to suggest that ECT causes similar long and short term effects to psychedelics in some in vivo case studies<ref>Psychotic symptoms as a complication of electroconvulsive therapy – a case report Anna Antosik-Wójcińska, Magdalena Chojnacka, Łukasz Święcicki Affective Disorders Unit, Second Department of Psychiatry, Institute of Psychiatry and Neurology in Warsaw</ref><ref>'''ECT associated musical hallucinations in an elderly patient''': a case report. ''Ann Gen Psychiatry'' 5, 10 (2006). Janakiraman, R., Wildgoose, K. & Seelam, K. <nowiki>https://doi.org/10.1186/1744-859X-5-10</nowiki></ref><ref>'''LSD-Like Flashbacks Associated with ECT'''. Convuls Ther. Russ MJ, Gold JM. . 1987;3(4):296-301. PMID: 11940932. Accessed on 4th July 2022 via: https://pubmed.ncbi.nlm.nih.gov/11940932/</ref>. | ||
=== Blue Marble Effect === | === Blue Marble Effect === | ||
Leland Melvin was saying “we need to send everyone to space so they can experience this overview effect” and it was frustrating, because as great an idea as that is, it’s extremely unrealistic in the short term. Yuri Gagarin, upon his return as the first human in space, marveled at the planet from orbit in 1961. “''People of the world, let us safeguard and enhance this beauty — not destroy it'',” . A half-century later, ex-NASA astronaut José Hernández said that the view aboard the Space Shuttle Discovery in 2009 turned him into “an instant treehugger.” On Christmas Eve 1968, the NASA astronauts Frank Borman, Jim Lovell and William Anders were aboard Apollo 8, the first manned mission to orbit the Moon. They had spent most of the day photographing the Moon’s surface, when Borman turned the spaceship around, and Earth came into view. ‘Oh my God, look at that picture over there. Here’s the Earth coming up,’ shouted Anders. Like the astronauts themselves, the world was awestruck by the first images of the whole Earth from space, which are today widely credited with triggering the birth of the modern environmental movement. | Leland Melvin was saying “we need to send everyone to space so they can experience this overview effect” and it was frustrating, because as great an idea as that is, it’s extremely unrealistic in the short term. Yuri Gagarin, upon his return as the first human in space, marveled at the planet from orbit in 1961. “''People of the world, let us safeguard and enhance this beauty — not destroy it'',” . A half-century later, ex-NASA astronaut José Hernández said that the view aboard the Space Shuttle Discovery in 2009 turned him into “an instant treehugger.” On Christmas Eve 1968, the NASA astronauts Frank Borman, Jim Lovell and William Anders were aboard Apollo 8, the first manned mission to orbit the Moon. They had spent most of the day photographing the Moon’s surface, when Borman turned the spaceship around, and Earth came into view. ‘Oh my God, look at that picture over there. Here’s the Earth coming up,’ shouted Anders. Like the astronauts themselves, the world was awestruck by the first images of the whole Earth from space, which are today widely credited with triggering the birth of the modern environmental movement. | ||
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===Stroboscopics=== | ===Stroboscopics=== | ||
Flicker light stimulation are capable of inducing visual effects with an intensity rated to be similar in strength to effects induced by psychedelic substances<ref>Altered states phenomena induced by visual flicker light stimulation. Marie Therese Bartossek,Johanna Kemmerer,Timo Torsten Schmidt. Published: July 1, 2021. <nowiki>https://doi.org/10.1371/journal.pone.0253779</nowiki></ref>. Whilst some visual aspects of the psychedelic experience can be replicated there is no evidence to suggest any other neurological effect occurs, [[Setting|click this link to see a range of psychedelic toys]] the strongest of which is a [https://strobe.cool/ stroboscopic]. Many of these techniques are thought to work by replicating the speed of specific brain wave patterns. It is thought that low hallucination-inducing frequencies (8 to 11 Hz) and high hallucination-inducing frequencies (19 to 25 Hz)<ref>'''''The hodology of hallucinations'''. FFYTCHE, D. (2008). Cortex, 44(8), 1067–1083.'' doi:10.1016/j.cortex.2008.04.005 </ref>. | Flicker light stimulation are capable of inducing visual effects with an intensity rated to be similar in strength to effects induced by psychedelic substances<ref>'''Altered states phenomena induced by visual flicker light stimulation'''. Marie Therese Bartossek, Johanna Kemmerer, Timo Torsten Schmidt. Published: July 1, 2021. <nowiki>https://doi.org/10.1371/journal.pone.0253779</nowiki></ref>. Whilst some visual aspects of the psychedelic experience can be replicated there is no evidence to suggest any other neurological effect occurs, [[Setting|click this link to see a range of psychedelic toys]] the strongest of which is a [https://strobe.cool/ stroboscopic]. Many of these techniques are thought to work by replicating the speed of specific brain wave patterns. It is thought that low hallucination-inducing frequencies (8 to 11 Hz) and high hallucination-inducing frequencies (19 to 25 Hz)<ref>'''''The hodology of hallucinations'''. FFYTCHE, D. (2008). Cortex, 44(8), 1067–1083.'' doi:10.1016/j.cortex.2008.04.005. Accessed on 17th September 2022 via: https://pubmed.ncbi.nlm.nih.gov/18586234/ </ref>. | ||
=== Optical Illusions === | === Optical Illusions === |