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=== Near Death Experience === | === Near Death Experience === | ||
A Near-death-experience (NDE) is classically described as an intense psychological experience characterized by an atypical state of consciousness occurring during an episode of apparent unconsciousness and usually in life-threatening conditions<ref>'''The phenomenology of near death experiences.''' ''Am. J. Psychiatry'' 137, 1193–1196. Greyson, B., and Stevenson, I. (1980).</ref>. NDEs in general are typically characterised by hallucinations<ref>'''Near-Death Experiences are Hallucinations'''. Keith Augustine. In Keith Augustine & Michael Martin (eds.), The Myth of an Afterlife: The Case against Life After Death. Rowman & Littlefield. pp. 529-569 (2015)</ref><ref>'''Three cases of near death experience''': Is it physiology, physics or philosophy? Purkayastha M, Mukherjee KK. Ann Neurosci. 2012 Jul;19(3):104-6. doi: 10.5214/ans.0972.7531.190303. PMID: 25205979; PMCID: PMC4117086.</ref> which are affected by set and setting much like psychedelics. Some evidence suggests that dissociatives such as ketamine<ref>'''The Ketamine Model of the Near-Death Experience''': A Central Role for the N-Methyl-D-Aspartate Receptor. Jansen, K.L.R. Journal of Near-Death Studies 16, 5–26 (1997). <nowiki>https://doi.org/10.1023/A:1025055109480</nowiki></ref> or classical psychedelics such as DMT can induce this state<ref>'''DMT Models the Near-Death Experience'''. Christopher Timmermann1,2*, Leor Roseman1,2, Luke Williams1, David Erritzoe1, Charlotte Martial3, Héléna Cassol3, Steven Laureys3, David Nutt1 and Robin Carhart-Harris. Front. Psychol., 15 August 2018 | <nowiki>https://doi.org/10.3389/fpsyg.2018.01424</nowiki> </ref> however historically, a defunct class of drugs called the pseudohallucinogens<ref>Schultes, Richard Evans (1976). Hallucinogenic Plants. illus. Elmer W. Smith. New York: Golden Press. <nowiki>ISBN 0-307-24362-1</nowiki>.</ref> is thought to bridge this gap. However pseudohallucinogens do not have the same tryptamine / phenylethylamine chemical structures as the classical psychedelics instead they include drugs with a diverse range of effects which broadly are considered poisonous, these include: | A Near-death-experience (NDE) is classically described as an intense psychological experience characterized by an atypical state of consciousness occurring during an episode of apparent unconsciousness and usually in life-threatening conditions<ref>'''The phenomenology of near death experiences.''' ''Am. J. Psychiatry'' 137, 1193–1196. Greyson, B., and Stevenson, I. (1980).</ref>. NDEs in general are typically characterised by hallucinations<ref>'''Near-Death Experiences are Hallucinations'''. Keith Augustine. In Keith Augustine & Michael Martin (eds.), The Myth of an Afterlife: The Case against Life After Death. Rowman & Littlefield. pp. 529-569 (2015)</ref><ref>'''Three cases of near death experience''': Is it physiology, physics or philosophy? Purkayastha M, Mukherjee KK. Ann Neurosci. 2012 Jul;19(3):104-6. doi: 10.5214/ans.0972.7531.190303. PMID: 25205979; PMCID: PMC4117086.</ref> which are affected by set and setting much like psychedelics<ref>'''Comparison of psychedelic and near-death or other non-ordinary experiences in changing attitudes about death and dying'''. Mary M. Sweeney ,Sandeep Nayak,Ethan S. Hurwitz, Lisa N. Mitchell,T. Cody Swift,Roland R. Griffiths. Published: August 24, 2022. Accessed on 26th August 2022 via <nowiki>https://doi.org/10.1371/journal.pone.0271926</nowiki></ref>. Some evidence suggests that dissociatives such as ketamine<ref>'''The Ketamine Model of the Near-Death Experience''': A Central Role for the N-Methyl-D-Aspartate Receptor. Jansen, K.L.R. Journal of Near-Death Studies 16, 5–26 (1997). <nowiki>https://doi.org/10.1023/A:1025055109480</nowiki></ref> or classical psychedelics such as DMT can induce this state<ref>'''DMT Models the Near-Death Experience'''. Christopher Timmermann1,2*, Leor Roseman1,2, Luke Williams1, David Erritzoe1, Charlotte Martial3, Héléna Cassol3, Steven Laureys3, David Nutt1 and Robin Carhart-Harris. Front. Psychol., 15 August 2018 | <nowiki>https://doi.org/10.3389/fpsyg.2018.01424</nowiki> </ref> however historically, a defunct class of drugs called the pseudohallucinogens<ref>Schultes, Richard Evans (1976). Hallucinogenic Plants. illus. Elmer W. Smith. New York: Golden Press. <nowiki>ISBN 0-307-24362-1</nowiki>.</ref> is thought to bridge this gap. However, pseudohallucinogens do not have the same tryptamine / phenylethylamine chemical structures as the classical psychedelics instead they include drugs with a diverse range of effects which broadly are considered poisonous, these include: | ||
* Nutmeg / mace | * Nutmeg / mace | ||