2,762
edits
No edit summary |
|||
Line 57: | Line 57: | ||
== Microdosing == | == Microdosing == | ||
The medical definition of ''microdosing'' is a dose given which is ''sub therapeutic'', i.e. does not have any discernible effect. However, thousands of users claim that very low doses of LSD, taken at 3–4-day intervals, improve mood and cognitive function. In control studies, in the absence of placebo, microdosing has been shown to be a figment of imagination many times over in numerous studies<ref>Repeated low doses of LSD in healthy adults: A placebo-controlled, dose–response study Harriet de Wit,Hanna M. Molla,Anya Bershad,Michael Bremmer,Royce Lee First published: 01 February 2022 <nowiki>https://doi.org/10.1111/adb.13143</nowiki>https://onlinelibrary.wiley.com/doi/abs/10.1111/adb.13143</ref> | The medical definition of ''microdosing'' is a dose given which is ''sub therapeutic'', i.e. does not have any discernible effect. However, thousands of users claim that very low doses of LSD, taken at 3–4-day intervals, improve mood and cognitive function. In control studies, in the absence of placebo, microdosing has been shown to be a figment of imagination many times over in numerous studies<ref>Repeated low doses of LSD in healthy adults: A placebo-controlled, dose–response study Harriet de Wit,Hanna M. Molla,Anya Bershad,Michael Bremmer,Royce Lee First published: 01 February 2022 <nowiki>https://doi.org/10.1111/adb.13143</nowiki>https://onlinelibrary.wiley.com/doi/abs/10.1111/adb.13143</ref> This may be due to the fact that the main part of the effect of psychedelics is the subjective effects caused by them, i.e. the experience of the trip is more important than the underlying chemical electrical mechanisms.<ref>The Subjective Effects of Psychedelics Are Necessary for Their Enduring Therapeutic Effects: David B. Yaden and Roland R. Griffiths* ACS Pharmacol. Transl. Sci. 2021, 4, 2, 568–572. Publication Date:December 10, 2020. <nowiki>https://doi.org/10.1021/acsptsci.0c00194</nowiki></ref> | ||
'''References''' | '''References''' |