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=== Norbaeocystin === | === Norbaeocystin === | ||
Norbaeocystin (C10H13N2O4P) is another alkaloid found in magic mushrooms, with characteristics and effects similar to those of baeocystin. Both compounds are derivatives of 4-phosphoryloxytryptamine and analogs of psilocybin, although the former is considered a monomethyl analog, and the latter is a demethyl analog. | Norbaeocystin (C10H13N2O4P) is another alkaloid found in magic mushrooms, with characteristics and effects similar to those of baeocystin. Both compounds are derivatives of 4-phosphoryloxytryptamine and analogs of psilocybin, although the former is considered a monomethyl analog, and the latter is a demethyl analog. It is thought that norbaeocystin, may share overlapping therapeutic potential with psilocybin, but without causing hallucinations<ref>'''Pharmacological and behavioural effects of tryptamines present in psilocybin-containing mushrooms'''. Ryan J. Rakoczy, Grace N. Runge, Abhishek K. Sen, Oscar Sandoval, Hunter G. Wells, Quynh Nguyen, Brianna R. Roberts, Jon H. Sciortino, William J. Gibbons Jr, Lucas M. Friedberg. First published: 02 June 2024 https://doi.org/10.1111/bph.16466</ref>. | ||
=== Norpsilocin === | === Norpsilocin === | ||
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== Dose == | == Dose == | ||
Depending on the strain and storage condition (as above) the most common dose is between 1 and 2 grams of dried mushrooms. In regards to [[psilocybin]] dosages, in general a therapeutic dose is considered 25mg which is equivalent to 2.5 grams of dried mushrooms. Popularised by the ethnobotanist Terence McKenna a “''heroic dose''” A is gram or more and are strong enough to take you out of your present reality. | Depending on the strain and storage condition (as above) the most common dose is between 1 and 2 grams of dried mushrooms. In regards to [[psilocybin]] dosages, in general a therapeutic dose is considered 25mg which is equivalent to 2.5 grams of dried mushrooms. Popularised by the ethnobotanist Terence McKenna a “''heroic dose''” A is gram or more and are strong enough to take you out of your present reality. | ||
== Combination Therapy == | |||
By combining psilocybin with other compounds it is theoretically possible to decrease adverse effects whilst maintaining or increasing desired effects. Below is a list of medicines thought to compliment psilocybin therapy: | |||
* '''Niacin''' - in combination with psilocybin is termed the Stamets Stack. | |||
* '''[[MDMA]]''' - in combination with psilocybin is termed a [[Hippie Flip|hippie flip]]. | |||
'''References''' | '''References''' | ||
<references /> | <references /> |