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== Microdosing == | == Microdosing == | ||
[[File:Psychedelics exert their effect experientially effect.png|alt=Psychedelics exert their effect experientially|thumb|'''Figure 3.''' Psychedelics exert their effect experientially]] | [[File:Psychedelics exert their effect experientially effect.png|alt=Psychedelics exert their effect experientially|thumb|'''Figure 3.''' Psychedelics exert their effect experientially]] | ||
The medical definition of ''microdosing'' is a dose given which is ''sub therapeutic'', i.e. does not have any discernible effect. However, | The medical definition of ''microdosing'' is a dose given which is ''sub therapeutic'', i.e. does not have any discernible effect. However, many claim that very low doses of LSD, taken at 3–4-day intervals, improve mood and cognitive function. In controlled studies, which are superior to anecdotal studies, (see [[Referencing|critical appraisal]]) where the placebo effect is excluded microdosing has been disproven<ref>'''Repeated low doses of LSD in healthy adults: A placebo-controlled, dose–response study''' Harriet de Wit,Hanna M. Molla,Anya Bershad,Michael Bremmer,Royce Lee First published: 01 February 2022 <nowiki>https://doi.org/10.1111/adb.13143</nowiki>https://onlinelibrary.wiley.com/doi/abs/10.1111/adb.13143</ref>. It has been suggested that this is because the experience of the ''trip'' is more important than the underlying chemical-electrical mechanisms.<ref>'''The Subjective Effects of Psychedelics Are Necessary for Their Enduring Therapeutic Effects''': David B. Yaden and Roland R. Griffiths* ACS Pharmacol. Transl. Sci. 2021, 4, 2, 568–572. Publication Date:December 10, 2020. <nowiki>https://doi.org/10.1021/acsptsci.0c00194</nowiki></ref><hr> | ||