Ketamine: Difference between revisions
From BurnZero
mNo edit summary |
mNo edit summary |
||
| Line 1: | Line 1: | ||
'''Ketamine has been used as a general anaesthetic for more than 50 years'''. The medicine has recently garnered prominence as a therapeutic agent used in the treatment of depression<ref>Zhang K, Hashimoto K. An update on ketamine and its two enantiomers as rapid-acting antidepressants. Expert Rev Neurother. 2019 Jan;19(1):83-92. doi: 10.1080/14737175.2019.1554434. Epub 2018 Dec 4. PMID: 30513009.</ref>. | '''Ketamine has been used as a general anaesthetic for more than 50 years'''. The medicine has recently garnered prominence as a therapeutic agent used in the treatment of depression<ref>Zhang K, Hashimoto K. An update on ketamine and its two enantiomers as rapid-acting antidepressants. Expert Rev Neurother. 2019 Jan;19(1):83-92. doi: 10.1080/14737175.2019.1554434. Epub 2018 Dec 4. PMID: 30513009.</ref>. | ||
== Effects == | |||
Ketamine has been shown to cause: | |||
* Dissociation with some patients reporting [[Out of Body Experiences]] | |||
* neurocognitive effects | |||
=== Abuse === | |||
Like any drug, overuse is linked to negative effects. It has been found that chronic, uncontrolled use may lead to ketamine-induced ulcerative cystitis and neurocognitive impairment which can impact negatively upon achievement in education and at work, and also compound addiction problems.<ref>Morgan CJ, Curran HV; Independent Scientific Committee on Drugs. Ketamine use: a review. Addiction. 2012 Jan;107(1):27-38. doi: 10.1111/j.1360-0443.2011.03576.x. Epub 2011 Jul 22. PMID: 21777321.</ref> | Like any drug, overuse is linked to negative effects. It has been found that chronic, uncontrolled use may lead to ketamine-induced ulcerative cystitis and neurocognitive impairment which can impact negatively upon achievement in education and at work, and also compound addiction problems.<ref>Morgan CJ, Curran HV; Independent Scientific Committee on Drugs. Ketamine use: a review. Addiction. 2012 Jan;107(1):27-38. doi: 10.1111/j.1360-0443.2011.03576.x. Epub 2011 Jul 22. PMID: 21777321.</ref> | ||
Revision as of 01:47, 6 December 2022
Ketamine has been used as a general anaesthetic for more than 50 years. The medicine has recently garnered prominence as a therapeutic agent used in the treatment of depression[1].
Effects
Ketamine has been shown to cause:
- Dissociation with some patients reporting Out of Body Experiences
- neurocognitive effects
Abuse
Like any drug, overuse is linked to negative effects. It has been found that chronic, uncontrolled use may lead to ketamine-induced ulcerative cystitis and neurocognitive impairment which can impact negatively upon achievement in education and at work, and also compound addiction problems.[2]
- ↑ Zhang K, Hashimoto K. An update on ketamine and its two enantiomers as rapid-acting antidepressants. Expert Rev Neurother. 2019 Jan;19(1):83-92. doi: 10.1080/14737175.2019.1554434. Epub 2018 Dec 4. PMID: 30513009.
- ↑ Morgan CJ, Curran HV; Independent Scientific Committee on Drugs. Ketamine use: a review. Addiction. 2012 Jan;107(1):27-38. doi: 10.1111/j.1360-0443.2011.03576.x. Epub 2011 Jul 22. PMID: 21777321.