Psychedelics: Difference between revisions

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== Mechanism of Action ==
== Mechanism of Action ==
[[File:Psychedelic Biochemistry.png|thumb|'''Figure 4'''. The neurochemical activity of various psychedelics.]]
[[File:Psychedelic Biochemistry.png|thumb|'''Figure 4'''. The neurochemical activity of various psychedelics.]]
Psychedelics induce [[Neuroplasticity|neuroplastic]], [[Pivotal mental state|pivotal mental states]]. It is thought psychedelics mediate this effect by altering the Brain-Derived Neurotrophic Factor (BDNF)<ref>'''Psychedelics and Neuroplasticity: A Systematic Review Unraveling the Biological Underpinnings of Psychedelics''' Cato M. H. de Vos, Natasha L. Mason and Kim P. C. Kuypers* Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands Front. Psychiatry, 10 September 2021 </ref> receptor TrkB<ref>'''Psychedelics promote plasticity by directly binding to BDNF receptor TrkB'''. Rafael Moliner, Mykhailo Girych. Published: 05 June 2023 in Nature Neuroscience. Accessed on 8 Jun 2023 via: <nowiki>https://www.nature.com/articles/s41593-023-01316-5</nowiki></ref>.
Psychedelics induce [[Neuroplasticity|neuroplastic]], [[Pivotal mental state|pivotal mental states]]. It is thought psychedelics mediate this effect by activating 5HT2A and tyrosine kinase receptors causing the release of Brain-Derived Neurotrophic Factor (BDNF)<ref>'''Psychedelics and Neuroplasticity: A Systematic Review Unraveling the Biological Underpinnings of Psychedelics''' Cato M. H. de Vos, Natasha L. Mason and Kim P. C. Kuypers* Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands Front. Psychiatry, 10 September 2021 </ref> receptor TrkB<ref>'''Psychedelics promote plasticity by directly binding to BDNF receptor TrkB'''. Rafael Moliner, Mykhailo Girych. Published: 05 June 2023 in Nature Neuroscience. Accessed on 8 Jun 2023 via: <nowiki>https://www.nature.com/articles/s41593-023-01316-5</nowiki></ref>.


== Psychedelic Comparison ==
== Psychedelic Comparison ==

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