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Hallucinogen Persisting Perception Disorder: Difference between revisions
Hallucinogen Persisting Perception Disorder (view source)
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'''Hallucinogen Persisting Perception Disorder (HPPD) is a rare clinical condition in which patients who have had previous exposure to a hallucinogenic substance continue to experience perceptual distortions months to years after complete cessation of the initial substance use.''' | '''Hallucinogen Persisting Perception Disorder (HPPD) is a rare clinical condition in which patients who have had previous exposure to a hallucinogenic substance continue to experience perceptual distortions months to years after complete cessation of the initial substance use.''' | ||
Currently, there is no standardized treatment for HPPD. However, some interventions show promise, including lamotrigine, benzodiazepines, and non-invasive brain stimulation. Research on these treatments is limited due to the rarity of the condition and the variability of its symptoms. | |||
==== Prevalence ==== | |||
HPPD is considered an uncommon outcome of psychedelic use. One study estimates the prevalence at about 4.2% among hallucinogen users, specifically referencing data from the American Psychiatric Association<ref>Hadley, M., Halliday, A., & Stone, J. (2023). Association of Hallucinogen Persisting Perception Disorder with Trait Neuroticism and Mental Health Symptoms.. ''Journal of psychoactive drugs'', 1-7 . <nowiki>https://doi.org/10.1080/02791072.2023.2287081</nowiki>.</ref><ref>Nutting, S., Bruinsma, T., Anderson, M., & Jolly, T. (2020). Psychotic and Still Tripping—Hallucinogen Persisting Perception Disorder and First Break Psychosis in an Adolescent. ''International Journal of Mental Health and Addiction''. [[/doi.org/10.1007/s11469-020-00338-5|https://doi.org/10.1007/s11469-020-00338-5]].</ref>. | |||
HPPD has been observed more frequently in adolescents who use [[psychedelics]]<ref>https://www.frontiersin.org/articles/10.3389/frcha.2024.1364617/abstract</ref>. After a single use of substances such as [[LSD]], [[psilocybin]], or [[cannabis]], individuals are at an increased risk of developing HPPD. The condition appears to be more common among those with a history of psychological disorders or substance misuse, though its precise neurological mechanisms remain unclear. | HPPD has been observed more frequently in adolescents who use [[psychedelics]]<ref>https://www.frontiersin.org/articles/10.3389/frcha.2024.1364617/abstract</ref>. After a single use of substances such as [[LSD]], [[psilocybin]], or [[cannabis]], individuals are at an increased risk of developing HPPD. The condition appears to be more common among those with a history of psychological disorders or substance misuse, though its precise neurological mechanisms remain unclear. | ||
'''References''' | '''References''' | ||