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Psychedelic Therapy Inclusion and Exclusion Criteria: Difference between revisions
Psychedelic Therapy Inclusion and Exclusion Criteria (view source)
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Certain types of patient are more at risk of adverse side effects to [[Psychedelics|psychedelic]] medicine. Therefore, a judgement needs to be made pre-administration to recommend to the patient where it is safe to take the medicine or not. In the vast majority of cases the benefits of taking psychedelics outweighs the potential risks. However, in general, there are certain psychedelic exclusion criteria which would mean someone should not be immediately recommended therapy, these include: | '''Certain types of patient are more at risk of adverse side effects to [[Psychedelics|psychedelic]] medicine. Therefore, a judgement needs to be made pre-administration to recommend to the patient where it is safe to take the medicine or not.''' We have created a [[Psychedelic Therapy Risk Analysis Tool]] to aid in this determination. | ||
In the vast majority of cases the benefits of taking psychedelics outweighs the potential risks. However, in general, there are certain psychedelic exclusion criteria which would mean someone should not be immediately recommended therapy, these include: | |||
* People taking '''Kentanserin''' (a rare research chemical) or '''olanzapine''' (an atypical antipsychotic) as they can can [[Trip Terminator|''terminate'' a trip]]. | * People taking '''Kentanserin''' (a rare research chemical) or '''olanzapine''' (an atypical antipsychotic) as they can can [[Trip Terminator|''terminate'' a trip]]. | ||
* There is some evidence to suggest people with history of '''psychosis' ''should not take psychedelics; Quite ironically Aldous Huxley - the man who co-created the word''''' '' | * There is some evidence to suggest people with history of '''psychosis' ''should not take psychedelics;''''' Quite ironically, Aldous Huxley - the man who co-created the word "''psychedel''<nowiki/>''ic''', had a brother with bipolar disorder and a history of psychosis in his family,- would be screened out of most psychedelic trials and clinics today. | ||
* Presence or history of '''mania''' or '''bipolar disorder.''' | * Presence or history of '''mania, personality''' or '''bipolar disorder.''' | ||
More specifically, taking the most recent clinical trials<ref>'''Psilocybin for treatment resistant depression in patients taking a concomitant SSRI medication.''' '''Goodwin, G.M., Croal, M., Feifel, D. ''et al.''''' ''Neuropsychopharmacol.'' (2023). Accessed 15 Jul 2023 via <nowiki>https://www.nature.com/articles/s41386-023-01648-7</nowiki></ref> below is a composite of | More specifically, taking the most recent clinical trials<ref>'''Psilocybin for treatment resistant depression in patients taking a concomitant SSRI medication.''' '''Goodwin, G.M., Croal, M., Feifel, D. ''et al.''''' ''Neuropsychopharmacol.'' (2023). Accessed 15 Jul 2023 via <nowiki>https://www.nature.com/articles/s41386-023-01648-7</nowiki></ref> into account, below is a composite of Best Practice. | ||
== Inclusion Criteria == | == Inclusion Criteria == | ||
Participants meeting all the following inclusion criteria at Screening were considered for admission into the study. | Participants meeting all the following inclusion criteria at Screening were considered for admission into the study. | ||
1. Signed Informed Consent | 1. Signed Informed Consent. | ||
2. 18 years of age or older at Screening. | 2. 18 years of age or older at Screening. | ||
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== Notable Omissions == | == Notable Omissions == | ||
'''SSRIs (Selective Serotonin Reuptake Inhibitors) and [[psychedelics]] do not have a strong enough interaction that could lead to serotonin syndrome, a serious and potentially life-threatening condition.''' However, research has indicated that there is a mild interaction between psychedelics and antidepressants, such as SSRIs, which may reduce the effectiveness of the psychedelics. For more information, read the following article on the interaction between [[SSRI and psychedelics|'''SSRIs''' and psychedelic]]<nowiki/>s. | |||
'''Reference''' | '''Reference''' | ||