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All medicines, when administered without proper guidance can cause adverse effects | '''All medicines, when administered without proper guidance can cause adverse effects'''<ref>'''Adverse effects of psychedelics: From anecdotes and misinformation to systematic science'''. Schlag AK, Aday J, Salam I, Neill JC, Nutt DJ. Journal of Psychopharmacology. 2022;36(3):258-272. doi:10.1177/02698811211069100</ref>. Therefore, it is essential, before administering any medicine to understand that there are specific categories of people who are more prone to experiencing negative effects. These can be seen within the most up to date [[Psychedelic Therapy Inclusion and Exclusion Criteria|psychedelic therapy inclusion / exclusion criteria]] set by medical professionals in clinical trials. | ||
However, not everyone who might experience negative effects can and should be screened out. Below is a list of general and then specific potential adverse effects to [[psychedelics]]. | |||
== General Psychedelic Adverse Effects == | |||
=== Flashbacks === | === Flashbacks === | ||
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Hallucinogen Persisting Perception Disorder (HPPD) is a rare clinical condition in which patients who have had previous exposure to a hallucinogenic substance continue to experience perceptual distortions months to years after complete cessation of the initial substance use. HPPD is listed in the Diagnostic and Statistical Manual of Mental Disorders (DSM-V). | Hallucinogen Persisting Perception Disorder (HPPD) is a rare clinical condition in which patients who have had previous exposure to a hallucinogenic substance continue to experience perceptual distortions months to years after complete cessation of the initial substance use. HPPD is listed in the Diagnostic and Statistical Manual of Mental Disorders (DSM-V). | ||
== Drug Specific Effects == | |||
==== Mescaline ==== | ==== Mescaline ==== | ||
Mescaline can cause stomach cramps. | Mescaline can cause stomach cramps. | ||
== Psychedelic Adverse Effect Resistance == | |||
Age has been found to be negatively correlated with intensity of challenging experience<ref>'''Predicting the Intensity of Psychedelic-Induced Mystical and Challenging Experience in a Healthy Population: An Exploratory Post-Hoc Analysis'''. Neuropsychiatr Dis Treat. 2023; 19: 2105–2113. Published online 2023 Oct 5. Accessed on 16th October 2023 via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561760/</ref>. | |||
'''References''' | '''References''' |