Pivotal Mental States: Difference between revisions

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When people think of Electroconvulsive Therapy (ECT) they often think of the process depicted in the film ''One Flew Over the Cuckoo's Nest. A lone patient with electrodes attached to their head convulsing in pain... T''his was an over dramatisation, the modern process is far from what was depicted. Since its introduction in the 1930's, various changes to pulse width, dosing and duration, electrode placement and anesthesia have made the treatment almost unrecognisable<ref>'''Electroconvulsive therapy: a selected review'''. ''Am J Geriatr Psychiatry''. Greenberg RM, Kellner CH.  2005;13(4):268–81.</ref>. Research has shown that 64% to 87% of patients with severe MDD respond to ECT, with response rates as high as 95% for patients with MDD with psychotic features<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193538/</ref>. Furthermore, in otherwise healthy patients with intellectual disability, a retrospective chart review performed at Cambridge university has shown that 79% showed a positive outcome following ECT<ref>https://www.cambridge.org/core/journals/the-psychiatrist/article/use-of-ect-in-patients-with-an-intellectual-disability-review/B2CD9151E5A2B9462BD80175E63A9CB0</ref>. There is some evidence to suggest that ECT causes similar long and short term effects to psychedelics in some in vivo case studies<ref>Psychotic symptoms as a complication of electroconvulsive therapy – a case report Anna Antosik-Wójcińska, Magdalena Chojnacka, Łukasz Święcicki Affective Disorders Unit, Second Department of Psychiatry, Institute of Psychiatry and Neurology in Warsaw</ref><ref>'''ECT associated musical hallucinations in an elderly patient''': a case report. ''Ann Gen Psychiatry'' 5, 10 (2006). Janakiraman, R., Wildgoose, K. & Seelam, K.  <nowiki>https://doi.org/10.1186/1744-859X-5-10</nowiki></ref><ref>'''LSD-Like Flashbacks Associated with ECT'''. Convuls Ther. Russ MJ, Gold JM. . 1987;3(4):296-301. PMID: 11940932. Accessed on 4th July 2022 via: https://pubmed.ncbi.nlm.nih.gov/11940932/</ref>.
When people think of Electroconvulsive Therapy (ECT) they often think of the process depicted in the film ''One Flew Over the Cuckoo's Nest. A lone patient with electrodes attached to their head convulsing in pain... T''his was an over dramatisation, the modern process is far from what was depicted. Since its introduction in the 1930's, various changes to pulse width, dosing and duration, electrode placement and anesthesia have made the treatment almost unrecognisable<ref>'''Electroconvulsive therapy: a selected review'''. ''Am J Geriatr Psychiatry''. Greenberg RM, Kellner CH.  2005;13(4):268–81.</ref>. Research has shown that 64% to 87% of patients with severe MDD respond to ECT, with response rates as high as 95% for patients with MDD with psychotic features<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193538/</ref>. Furthermore, in otherwise healthy patients with intellectual disability, a retrospective chart review performed at Cambridge university has shown that 79% showed a positive outcome following ECT<ref>https://www.cambridge.org/core/journals/the-psychiatrist/article/use-of-ect-in-patients-with-an-intellectual-disability-review/B2CD9151E5A2B9462BD80175E63A9CB0</ref>. There is some evidence to suggest that ECT causes similar long and short term effects to psychedelics in some in vivo case studies<ref>Psychotic symptoms as a complication of electroconvulsive therapy – a case report Anna Antosik-Wójcińska, Magdalena Chojnacka, Łukasz Święcicki Affective Disorders Unit, Second Department of Psychiatry, Institute of Psychiatry and Neurology in Warsaw</ref><ref>'''ECT associated musical hallucinations in an elderly patient''': a case report. ''Ann Gen Psychiatry'' 5, 10 (2006). Janakiraman, R., Wildgoose, K. & Seelam, K.  <nowiki>https://doi.org/10.1186/1744-859X-5-10</nowiki></ref><ref>'''LSD-Like Flashbacks Associated with ECT'''. Convuls Ther. Russ MJ, Gold JM. . 1987;3(4):296-301. PMID: 11940932. Accessed on 4th July 2022 via: https://pubmed.ncbi.nlm.nih.gov/11940932/</ref>.
=== Blue Marble Effect ===
=== Blue Marble Effect ===
Astronauts looking down on Earth from above for the first time see that only a fine blue line of atmosphere shelters our planet from the hostile vacuum of space — and often, they suddenly get an overwhelming responsibility to protect it. National borders disappear; the scene evokes a feeling of cosmic connection. This so-called “''overview effect''” has been turning astronauts into environmental advocates ever since the first person in space.
Astronauts looking back at Earth with the naked eye often suddenly get an overwhelming responsibility to protect it. When they see only a fine blue line of atmosphere shelters our only planet from the hostile vacuum of space, national borders disappear; and the scene often evokes a feeling of cosmic connection. This so-called “''overview effect''” has been turning astronauts into environmental advocates ever since the first person in space.


Yuri Gagarin, upon his return as the first human in space, marveled at the planet from orbit in 1961. “''People of the world, let us safeguard and enhance this beauty — not destroy it'',” . A half-century later, ex-NASA astronaut José Hernández said that the view aboard the Space Shuttle Discovery in 2009 turned him into “''an instant treehugger''.” On Christmas Eve 1968, the NASA astronauts Frank Borman, Jim Lovell and William Anders were aboard Apollo 8, the first manned mission to orbit the Moon. They had spent most of the day photographing the Moon’s surface, when Borman turned the spaceship around, and Earth came into view. ‘Oh my God, look at that picture over there. Here’s the Earth coming up,’ shouted Anders. Like the astronauts themselves, the world was awestruck by the first images of the whole Earth from space, which are today widely credited with triggering the birth of the modern environmental movement.
Yuri Gagarin, upon his return as the first human in space, marveled at the planet from orbit in 1961. “''People of the world, let us safeguard and enhance this beauty — not destroy it'',” . A half-century later, ex-NASA astronaut José Hernández said that the view aboard the Space Shuttle Discovery in 2009 turned him into “''an instant treehugger''.” On Christmas Eve 1968, the NASA astronauts Frank Borman, Jim Lovell and William Anders were aboard Apollo 8, the first manned mission to orbit the Moon. They had spent most of the day photographing the Moon’s surface, when Borman turned the spaceship around, and Earth came into view. ‘Oh my God, look at that picture over there. Here’s the Earth coming up,’ shouted Anders. Like the astronauts themselves, the world was awestruck by the first images of the whole Earth from space, which are today widely credited with triggering the birth of the modern environmental movement.
===Spiritual experiences===
===Spiritual experiences===
Whilst unproven scientifically, (it would be very difficult due to the subjective nature) spiritual experiences in some cases have been able to shift modes of general thought patterns. Pharmacologically the human brain has been found to produce psychedelic compounds, the thought is that certain techniques may be helpful in unleashing its endogenous effect:
Whilst unproven scientifically, (it would be very difficult due to the subjective nature) spiritual experiences have been shown to shift modes of general thought patterns. Pharmacologically the human brain has been found to produce psychedelic compounds, some believe that certain techniques may be helpful in unleashing its endogenous effect:
*'''Holotropic breathing techniques'''<ref>https://maps.org/news-letters/v23n1/v23n1_24-27.pdf</ref><ref>https://www.frontiersin.org/articles/10.3389/fnhum.2018.00353/full</ref>- 30 minutes breathing in a controlled, three-beat pattern — one sharp breath into my belly, one sharp breath into my lungs, and a sigh-like exhale to release.
*'''Holotropic breathing techniques'''<ref>https://maps.org/news-letters/v23n1/v23n1_24-27.pdf</ref><ref>https://www.frontiersin.org/articles/10.3389/fnhum.2018.00353/full</ref>- 30 minutes breathing in a controlled, three-beat pattern — one sharp breath into my belly, one sharp breath into my lungs, and a sigh-like exhale to release.



Revision as of 08:38, 24 September 2022

Pivotal mental states (PiMS) are states of mind created by profound psychological events which shift modes of general thought patterns. PiMS are an evolved feature of human brains, they aid psychological transformation when actual or perceived environmental pressures demand this[1].

PiMS achieve this by inducing neuroplastic states which given the correct priming, setting and integration allows the user to eliminate out of date thought patterns and the strengthen healthier, more adapted thought patterns.

Chemically induced PiMS

Pivotal mental states induced by psychedelics
Figure 1. Pivotal mental states induced by psychedelics[2].

The quickest way to induce a PiMs is by the use of certain medicines.

Psychedelics

Psychedelics are chemicals that when administered correctly can safely shift normal thought patterns[3] (see Figure 1). This is achieved by causing brain function to be less constrained than usual by modulating the presence or absence of underlying anatomical connections[4]. There is a common misconception of psychedelics which exhibits medically as Psychedelic Anxiety Syndrome. Instead of psychedelics being detrimental to ones health there is a huge amount of evidence to suggest the opposite[5].

Oneirogens

Whilst not considered a classical psychedelic, oneirogens, are chemicals which might induce PiMs by enhancing dream states. They are unlike psychedelics as they seem to be less potent and work unconsciously.

Non chemically induced PiMs

Near Death Experience

A Near-death-experience (NDE) is an intense psychological experience characterized by an atypical state of consciousness usually in life-threatening conditions[6]. NDEs in general are typically characterised by Out of Body Experiences and hallucinations[7][8] which are affected by set and setting much like psychedelics[9]. Some evidence suggests that dissociatives such as ketamine[10][11] or classical psychedelics such as DMT can induce this state[12] however historically, a defunct class of drugs called the pseudohallucinogens[13] is also thought to bridge this gap by actually causing a near death experience! These compounds consist of a diverse range of chemicals the effects of which broadly are considered poisonous, these include:

  • Nutmeg / mace
  • Wisteria sinenis

Electroconvulsive Therapy

When people think of Electroconvulsive Therapy (ECT) they often think of the process depicted in the film One Flew Over the Cuckoo's Nest. A lone patient with electrodes attached to their head convulsing in pain... This was an over dramatisation, the modern process is far from what was depicted. Since its introduction in the 1930's, various changes to pulse width, dosing and duration, electrode placement and anesthesia have made the treatment almost unrecognisable[14]. Research has shown that 64% to 87% of patients with severe MDD respond to ECT, with response rates as high as 95% for patients with MDD with psychotic features[15]. Furthermore, in otherwise healthy patients with intellectual disability, a retrospective chart review performed at Cambridge university has shown that 79% showed a positive outcome following ECT[16]. There is some evidence to suggest that ECT causes similar long and short term effects to psychedelics in some in vivo case studies[17][18][19].

Blue Marble Effect

Astronauts looking back at Earth with the naked eye often suddenly get an overwhelming responsibility to protect it. When they see only a fine blue line of atmosphere shelters our only planet from the hostile vacuum of space, national borders disappear; and the scene often evokes a feeling of cosmic connection. This so-called “overview effect” has been turning astronauts into environmental advocates ever since the first person in space.

Yuri Gagarin, upon his return as the first human in space, marveled at the planet from orbit in 1961. “People of the world, let us safeguard and enhance this beauty — not destroy it,” . A half-century later, ex-NASA astronaut José Hernández said that the view aboard the Space Shuttle Discovery in 2009 turned him into “an instant treehugger.” On Christmas Eve 1968, the NASA astronauts Frank Borman, Jim Lovell and William Anders were aboard Apollo 8, the first manned mission to orbit the Moon. They had spent most of the day photographing the Moon’s surface, when Borman turned the spaceship around, and Earth came into view. ‘Oh my God, look at that picture over there. Here’s the Earth coming up,’ shouted Anders. Like the astronauts themselves, the world was awestruck by the first images of the whole Earth from space, which are today widely credited with triggering the birth of the modern environmental movement.

Spiritual experiences

Whilst unproven scientifically, (it would be very difficult due to the subjective nature) spiritual experiences have been shown to shift modes of general thought patterns. Pharmacologically the human brain has been found to produce psychedelic compounds, some believe that certain techniques may be helpful in unleashing its endogenous effect:

  • Holotropic breathing techniques[20][21]- 30 minutes breathing in a controlled, three-beat pattern — one sharp breath into my belly, one sharp breath into my lungs, and a sigh-like exhale to release.

Stroboscopics

A bright light which flashes at the same speed as the transmission rate of the optical nerve can induce visual hallucinations similar to effects induced by psychedelic substances[22]. It is thought that low hallucination-inducing frequencies (8 to 11 Hz) and high hallucination-inducing frequencies (19 to 25 Hz)[23]. Whilst the visual aspects of the psychedelic experience can be replicated, there is no evidence to suggest any other neurological effect occurs. The effects of Stroboscopics can be readily demonstrated via experiment or from the comfort of one's home using Psychedelic Visualisation Modulators, the strongest of which is the stroboscopic tool.

Optical Illusions

Whilst one of the weakest ways to induce of PiMS, optical illusions can provide a gateway for people to start to ask elementary questions about their perceptions and start them on the path to overcome their Psychedelic Anxiety Syndrome.


References

  1. Brouwer A, Carhart-Harris RL. Pivotal mental states. Journal of Psychopharmacology. 2021;35(4):319-352. doi:10.1177/0269881120959637
  2. Kolp, E., Friedman, H. L., Krupitsky, E., Jansen, K., Sylvester, M., Young, M. S., & Kolp, A. (2014). Ketamine psychedelic psychotherapy: Focus on its pharmacology, phenomenology, and clinical applications. International Journal of Transpersonal Studies, 33(2), 84–140.
  3. Kettner H, Gandy S, Haijen ECHM, Carhart-Harris RL. From Egoism to Ecoism: Psychedelics Increase Nature Relatedness in a State-Mediated and Context-Dependent Manner. Int J Environ Res Public Health. 2019 Dec 16;16(24):5147. doi: 10.3390/ijerph16245147. PMID: 31888300; PMCID: PMC6949937.
  4. Andrea I. Luppi, Robin L. Carhart-Harris, Leor Roseman, Ioannis Pappas, David K. Menon, Emmanuel A. Stamatakis, LSD alters dynamic integration and segregation in the human brain, NeuroImage, Volume 227, 2021, 117653, ISSN 1053-8119, https://doi.org/10.1016/j.neuroimage.2020.117653. (https://www.sciencedirect.com/science/article/pii/S1053811920311381)
  5. Adverse effects of psychedelics: From anecdotes and misinformation to systematic science. Anne K Schlag, Jacob Aday, Iram Salam. First Published February 2, 2022. https://doi.org/10.1177/02698811211069100
  6. The phenomenology of near death experiences. Am. J. Psychiatry 137, 1193–1196. Greyson, B., and Stevenson, I. (1980).
  7. Near-Death Experiences are Hallucinations. Keith Augustine. In Keith Augustine & Michael Martin (eds.), The Myth of an Afterlife: The Case against Life After Death. Rowman & Littlefield. pp. 529-569 (2015)
  8. Three cases of near death experience: Is it physiology, physics or philosophy? Purkayastha M, Mukherjee KK.  Ann Neurosci. 2012 Jul;19(3):104-6. doi: 10.5214/ans.0972.7531.190303. PMID: 25205979; PMCID: PMC4117086.
  9. Comparison of psychedelic and near-death or other non-ordinary experiences in changing attitudes about death and dying. Mary M. Sweeney ,Sandeep Nayak,Ethan S. Hurwitz, Lisa N. Mitchell,T. Cody Swift,Roland R. Griffiths. Published: August 24, 2022. Accessed on 26th August 2022 via https://doi.org/10.1371/journal.pone.0271926
  10. Anomalous Psychedelic Experiences: At the Neurochemical Juncture of the Humanistic and Parapsychological, Volume 62, Issue 2. Accessed on 15th September 2022 via: https://journals.sagepub.com/doi/full/10.1177/0022167820917767
  11. The Ketamine Model of the Near-Death Experience: A Central Role for the N-Methyl-D-Aspartate Receptor. Jansen, K.L.R. Journal of Near-Death Studies 16, 5–26 (1997). https://doi.org/10.1023/A:1025055109480
  12. DMT Models the Near-Death Experience. Christopher Timmermann1,2*, Leor Roseman1,2, Luke Williams1, David Erritzoe1, Charlotte Martial3, Héléna Cassol3, Steven Laureys3, David Nutt1 and Robin Carhart-Harris. Front. Psychol., 15 August 2018 | https://doi.org/10.3389/fpsyg.2018.01424
  13. Schultes, Richard Evans (1976). Hallucinogenic Plants. illus. Elmer W. Smith. New York: Golden Press. ISBN 0-307-24362-1.
  14. Electroconvulsive therapy: a selected review. Am J Geriatr Psychiatry. Greenberg RM, Kellner CH. 2005;13(4):268–81.
  15. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193538/
  16. https://www.cambridge.org/core/journals/the-psychiatrist/article/use-of-ect-in-patients-with-an-intellectual-disability-review/B2CD9151E5A2B9462BD80175E63A9CB0
  17. Psychotic symptoms as a complication of electroconvulsive therapy – a case report Anna Antosik-Wójcińska, Magdalena Chojnacka, Łukasz Święcicki Affective Disorders Unit, Second Department of Psychiatry, Institute of Psychiatry and Neurology in Warsaw
  18. ECT associated musical hallucinations in an elderly patient: a case report. Ann Gen Psychiatry 5, 10 (2006). Janakiraman, R., Wildgoose, K. & Seelam, K. https://doi.org/10.1186/1744-859X-5-10
  19. LSD-Like Flashbacks Associated with ECT. Convuls Ther. Russ MJ, Gold JM. . 1987;3(4):296-301. PMID: 11940932. Accessed on 4th July 2022 via: https://pubmed.ncbi.nlm.nih.gov/11940932/
  20. https://maps.org/news-letters/v23n1/v23n1_24-27.pdf
  21. https://www.frontiersin.org/articles/10.3389/fnhum.2018.00353/full
  22. Altered states phenomena induced by visual flicker light stimulation. Marie Therese Bartossek, Johanna Kemmerer, Timo Torsten Schmidt. Published: July 1, 2021. https://doi.org/10.1371/journal.pone.0253779
  23. The hodology of hallucinations. FFYTCHE, D. (2008). Cortex, 44(8), 1067–1083. doi:10.1016/j.cortex.2008.04.005. Accessed on 17th September 2022 via: https://pubmed.ncbi.nlm.nih.gov/18586234/

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